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"Nakashima, Mikiro" のプロフィール: 53件    link image

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発行 タイトル 著者 ダウンロード数
2008-05-01 Absorption and Distribution Characteristics of 5-Fluorouracil (5-FU) after an Application to the Liver Surface in Rats in Order to Reduce Systemic Side Effects Kodama, Yukinobu; Fumoto, Shintaro; Nishi, Junya; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo; Nishida, Koyo 743
2004-11 Absorption characteristics of compounds with different molecular weights after application to the unilateral kidney surface in rats Nishida, Koyo; Tomiyama, Naoki; Mukai, Takahiro; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 1487
2005-08 Absorption characteristics of model compounds from the small intestinal serosal surface and a comparison with other organ surfaces Nishida, Koyo; Kuma, Akiko; Fumoto, Shintaro; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 1520
2002-07 Absorption characteristics of model compounds with different molecular weights from the serosal caecal surface in rats Nishida, Koyo; Nose, Seiichi; Kuma, Akiko; Mukai, Takahiro; Kawakami, Shigeru; Nakashima, Mikiro; Sasaki, Hitoshi; Toshiyuki, Sakaeda; Nakamura, Junzo 1096
2004-05 Absorption of phenolsulfonphthalein as a model across the mesenteric surface in rats to determine the drug absorption route after intraperitoneal administration Nishida, Koyo; Nose, Seiichi; Kuma, Akiko; Mukai, Takahiro; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 1141
2004-09 Antimicrobial Activity of Saturated Fatty Acids and Fatty Amines against Methicillin-Resistant Staphylococcus aureus Kitahara, Takashi; Koyama, Nao; Matsuda, Junichi; Aoyama, Yuko; Hirakata, Yoichi; Kamihira, Shimeru; Kohno, Shigeru; Nakashima, Mikiro; Sasaki, Hitoshi 942
2002-08 Biodistribution and Pharmacokinetics of O-Palmitoyl Tilisolol, a Lipophilic Prodrug of Tilisolol, after Intravenous Administration in Rats Kawakami, Shigeru; Ohshima, Nao; Hirayama, Ryu; Hirai, Masami; Kitahara, Takashi; Sakaeda, Toshiyuki; Mukai, Takahiro; Nishida, Koyo; Nakamura, Junzo; Nakashima, Mikiro; Sasaki, Hitoshi 736
2011-03 Case-controlled Study on Risk Factors for the Development of Constipation in Hospitalized Patients Ueki, Tetsuya; Nagai, Keiko; Ooe, Nobuharu; Nakashima, Mihoko N.; Nishida, Koyo; Nakamura, Junzo; Nakashima, Mikiro 1250
2007-09 Change in Pharmacokinetics of Model Compounds with Different Elimination Processes in Rats during Hypothermia Nishida, Koyo; Okazaki, Madoka; Sakamoto, Ryuichi; Inaoka, Natsuko; Miyake, Hideaki; Fumoto, Shintaro; Nakamura, Junzo; Nakashima, Mikiro; Sasaki, Hitoshi; Kakumoto, Mikio; Sakaeda, Toshiyuki 739
2011-08-01 Cross-sectional Study on Relationship between Constipation and Medication in Consideration of Sleep Disorder Ueki, Tetsuya; Nagai, Keiko; Mizukami, Yasuko; Takahashi, Akihiro; Ooe, Nobuharu; Nakashima, Mihoko N.; Nishida, Koyo; Nakamura, Junzo; Nakashima, Mikiro 562
2005-05 Delivery advantage to the unilateral kidney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model Nishida, Koyo; Kamenosono, Manabu; Kuma, Akiko; Fumoto, Shintaro; Mukai, Takahiro; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 2076
2012-03-01 Development of advanced pharmacy practice experience in national universities Ozawa, Koichiro; Sugawara, Mitsuru; Sekine, Yuko; Nakashima, Mikiro 989
2001-10 Effect of instillation method on the absorption of phenolsulphonphthalein as a model drug from the liver and small intestinal serosal surface in rats Nishida, Koyo; Yoshida, Yayoi; Mukai, Takahiro; Kawakami, Shigeru; Sakaeda, Toshiyuki; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 875
2005-11 Effect of Solution Composition of Plasmid DNA on Gene Transfection Following Liver Surface Administration in Mice Hirayama, Ryu; Fumoto, Shintaro; Nishida, Koyo; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 1050
2003-07 Effect of the Absorption Enhancer Saponin on the Intrarenal Distribution of 5-Fluorouracil Following Its Kidney Surface Application in Rats Nakamura, Junzo; Horimoto, Tomomi; Hirayama, Ryu; Mukai, Takahiro; Nakashima, Mikiro; Sasaki, Hitoshi; Nishida, Koyo 1175
2007-12 Electrophysiological Characterization of Tight Junctional Pathway of Rabbit Cornea Treated with Ophthalmic Ingredients Nakamura, Tadahiro; Yamada, Mikiko; Teshima, Mugen; Nakashima, Mikiro; To, Hideto; Ichikawa, Nobuhiro; Sasaki, Hitoshi 1003
2013-10 Evaluation for effect of hypothermia on the disposition of 4-nitrophenol in rats by in-vitro metabolism study and rat liver perfusion system Miyamoto, Hirotaka; Matsueda, Satoshi; Komori, Kotaro; Fumoto, Shintaro; Nakashima, Mikiro; Yoshikawa, Naoki; Hirata, Haruna; Shimokawa, Kenta; Ohwaki, Yuichi; Nishida, Koyo 226
2016-10-01 Evaluation for Peritoneal Injury at an Early Stage Using Dual Macromolecular Markers Hirata, Haruna; Fumoto, Shintaro; Miyamoto, Hirotaka; Nakashima, Mikiro; Nakayama, Morio; Nishida, Koyo 103
2015-10 Evaluation of hypothermia on the in vitro metabolism and binding and in vivo disposition of midazolam in rats Miyamoto, Hirotaka; Matsueda, Satoshi; Moritsuka, Akihiro; Shimokawa, Kenta; Hirata, Haruna; Nakashima, Mikiro; Sasaki, Hitoshi; Fumoto, Shintaro; Nishida, Koyo 138
2003-09 Evaluation of Newly Developed Oxygen Meters with Multi-Channels and Disposable Oxygen Electrode Sensors for Antimicrobial Susceptibility Testing Kitahara, Takashi; Koyama, Nao; Matsuda, Junichi; Hirakata, Yoichi; Kamihira, Shimeru; Kohno, Shigeru; Nakashima, Mikiro; Sasaki, Hitoshi 799
2003-12 Further Studies on the Kidney- and Site-Selective Delivery of 5-Fluorouracil Following Kidney Surface Application in Rats Nakamura, Junzo; Horimoto, Tomomi; Hirayama, Ryu; Mukai, Takahiro; Nakashima, Mikiro; Sasaki, Hitoshi; Nishida, Koyo 895
2008-12 Highly stomach-selective gene transfer following gastric serosal surface instillation of naked plasmid DNA in rats. Nishi, Junya; Fumoto, Shintaro; Ishii, Hiroki; Kodama, Yukinobu; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo; Nishida, Koyo 800
2008-06 Improved stomach selectivity of gene expression following microinstillation of plasmid DNA onto the gastric serosal surface in mice Nishi, Junya; Fumoto, Shintaro; Ishii, Hiroki; Kodama, Yukinobu; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo; Nishida, Koyo 891
1997-12-20 In Vivo Ocular Pharmacokinetic Model for Designing Dosage Schedules and Formulations of Ophthalmic Drugs in Human Sasaki, Hitoshi; Yamamura, Kenzo; Mukai, Takahiro; Nishida, Koyo; Nakamura, Junzo; Nakashima, Mikiro; Ogasawara, Masayoshi; Ichikawa, Masataka 1865
2005-06-30 Induction of Micronuclei in CHO Cells by Bleomycin but not by X-irradiation is Decreased by Treatment with HMG-CoA Reductase Inhibitors Iwashita, Junji; Kodama, Seiji; Nakashima, Mikiro; Sasaki, Hitoshi; Taniyama, Kotaro; Watanabe, Masami 507
2003-07 Influence of Liver Disease on Phenolsulfonphthalein Absorption from Liver Surface to Examine Possibility of Direct Liver Surface Application for Drug Targeting Nishida, Koyo; Honda, Tominori; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 597
2003-07 Influence of liver disease on phenolsulfonphthalein absorption from liver surface to examine possibility of direct liver surface application for drug targeting, Nishida, Koyo; Honda, Tominori; Nakashima, Mikiro; Sasaki, Hitoshi; Sakaeda, Toshiyuki; Nakamura, Junzo 444
2008-08 Influence of murine hepatitis induced by D-(+)-galactosamine hydrochloride and lipopolysaccharide on gene expression of polyethylenimine/plasmid DNA polyplex Miyanaga, Kei; Yoshioka, Takashi; Nakagawa, Hiroo; Kitahara, Takashi; To, Hideto; Ichikawa, Nobuhiro; Nakashima, Mikiro; Nishida, Koyo; Nakamura, Junzo; Sasaki, Hitoshi 685
2002-07 Kidney- and Site-Selective Delivery of 5-Fluorouracil Utilizing the Absorption on the Kidney Surface in Rats Kawakami, Shigeru; Horimoto, Tomomi; Nishida, Koyo; Hirayama, Ryu; Mukai, Takahiro; Nakashima, Mikiro; Sasaki, Hitoshi; Sakaeda, Toshiyuki; Nakamura, Junzo 1096
2004-10 Liver Site-Specific Gene Transfer Following the Administration of Naked Plasmid DNA to the Liver Surface in Mice Hirayama, Ryu; Nishida, Koyo; Fumoto, Shintaro; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 631
2009-07 Liver- and Lobe-Specific Gene Transfer Following the Continuous Microinstillation of Plasmid DNA onto the Liver Surface in Mice: Effect of Instillation Speed Fumoto, Shintaro; Tsuchimochi, Mayumi; Nishi, Junya; Ishii, Hiroki; Kodama, Yukinobu; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo; Nishida, Koyo 605
2014-02-01 Novel Diagnostic Method of Peritoneal Injury Using Dual Macromolecular Markers Hirata, Haruna; Miyamoto, Hirotaka; Shimokawa, Kenta; Nakashima, Mikiro; Nakayama, Morio; Fumoto, Shintaro; Nishida, Koyo 360
2002-11 A Novel Method for Preparation of Animal Models of Liver Damage: Liver Targeting of Carbon Tetrachloride in Rats Mukai, Takahiro; Mera, Kunihiro; Nishida, Koyo; Nakashima, Mikiro; Sasaki, Hitoshi; Sakaeda, Toshiyuki; Nakamura, Junzo 1090
2008-05-30 Ocular Pharmacokinetic/Pharmacodynamic Modeling for Multiple Anti-glaucoma Drugs Sakanaka, Koji; Kawazu, Kouichi; Tomonari, Masahide; Kitahara, Takashi; Nakashima, Mikiro; Nishida, Koyo; Nakamura, Junzo; Sasaki, Hitoshi; Higuchi, Shun 929
2008-05-01 Ocular Pharmacokinetic/Pharmacodynamic Modeling for Timolol in Rabbits Using a Telemetry System Sakanaka, Koji; Kawazu, Kouichi; Tomonari, Masahide; Kitahara, Takashi; Nakashima, Mikiro; Nishida, Koyo; Nakamura, Junzo; Sasaki, Hitoshi; Higuchi, Shun 714
2006-08 Partial Hepatectomy Enhances Polyethylenimine-Mediated Plasmid DNA Delivery Tada, Yuki; Kitahara, Takashi; Yoshioka, Takashi; Nakamura, Tadahiro; Ichikawa, Nobuhiro; Nakashima, Mikiro; Nishida, Koyo; Nakamura, Junzo; Sasaki, Hitoshi 768
2006-07 PEGylated Liposomes Loading Palmitoyl Prednisolone for Prolonged Blood Concentration of Prednisolone Teshima, Mugen; Kawakami, Shigeru; Fumoto, Shintaro; Nishida, Koyo; Nakamura, Junzo; Nakashima, Mikiro; Nakagawa, Hiroo; Ichikawa, Nobuhiro; Sasaki, Hitoshi 551
2004-04 Pharmacokinetics of Phenol Red in Rat Models of Liver Damage Prepared by Liver Targeting of Carbon Tetrachloride Mukai, Takahiro; Mera, Kunihiro; Nishida, Koyo; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 1015
2015-04 Quaternary Complexes Modified from pDNA and Poly-l-Lysine Complexes to Enhance pH-Buffering Effect and Suppress Cytotoxicity Kodama, Yukinobu; Yatsugi, Yuiko; Kitahara, Takashi; Kurosaki, Tomoaki; Egashira, Kanoko; Nakashima, Mikiro; Muro, Takahiro; Nakagawa, Hiroo; Higuchi, Norihide; Nakamura, Tadahiro; Sasaki, Hitoshi 251
2005-08 Regional delivery of model compounds and 5-Fluorouracil to the liver by their application to the liver surface in rats: its implication for clinical use Nishida, Koyo; Fujiwara, Rie; Kodama, Yukinobu; Fumoto, Shintaro; Mukai, Takahiro; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 1782
2011-09-01 Rubbing Gastric Serosal Surface Enhances Naked Plasmid DNA Transfer in Rats and Mice Mine, Toyoharu; Ishii, Hiroki; Nakajima, Sayuri; Yoshikawa, Naoki; Miyamoto, Hirotaka; Nakashima, Mikiro; Nakamura, Junzo; Fumoto, Shintaro; Nishida, Koyo 559
2010-01 Sensitive and Real-Time Method for Evaluating Corneal Barrier Considering Tear Flow Nakamura, Tadahiro; Teshima, Mugen; Kitahara, Takashi; Sasaki, Hitoshi; Uematsu, Masafumi; Kitaoka, Takashi; Nakashima, Mikiro; Nishida, Koyo; Nakamura, Junzo; Higuchi, Shun 597
2007-05 Spleen-Selective Gene Transfer Following the Administration of Naked Plasmid DNA onto the Spleen Surface in Mice Nakamura, Junzo; Fumoto, Shintaro; Kawanami, Rie; Kodama, Yukinobu; Nishi, Junya; Nakashima, Mikiro; Sasaki, Hitoshi; Nishida, Koyo 986
2005-06 Stomach- and Site-Selective Delivery of 5-Fluorouracil Following Its Application on the Gastric Serosal Surface in Rats Nakamura, Junzo; Kobayashi, Kazuko; Fumoto, Shintaro; Nishi, Junya; Mukai, Takahiro; Nakashima, Mikiro; Sasaki, Hitoshi; Nishida, Koyo 658
2006-10 Stomach-Selective Gene Transfer Following the Administration of Naked Plasmid DNA onto the Gastric Serosal Surface in Mice Nakamura, Junzo; Fumoto, Shintaro; Shoji, Keiko; Kodama, Yukinobu; Nishi, Junya; Nakashima, Mikiro; Sasaki, Hitoshi; Nishida, Koyo 934
2013-11-01 The Role of Fibronectin in Pulmonary Gene Transfer Following Intravenous Administration of Lipoplex in Mice Yoshikawa, Naoki; Fumoto, Shintaro; Nakashima, Mikiro; Shimokawa, Kenta; Miyamoto, Hirotaka; Nishida, Koyo 453
2006-04 Transport of Acebutolol through Rabbit Corneal Epithelium Kawazu, Kouichi; Oshita, Akemi; Nakamura, Tadahiro; Nakashima, Mikiro; Ichikawa, Nobuhiro; Sasaki, Hitoshi 856
2006-12 Transport of Timolol and Tilisolol in Rabbit Corneal Epithelium Sakanaka, Koji; Kawazu, Kouichi; Nishida, Koyo; Nakamura, Junzo; Nakashima, Mikiro; Nakamura, Tadahiro; Oshita, Akemi; Ichikawa, Nobuhiro; Sasaki, Hitoshi 599
2005-01 Unilateral Kidney-Selective Gene Transfer Following the Administration of Naked Plasmid DNA to the Kidney Surface in Mice Hirayama, Ryu; Nishida, Koyo; Fumoto, Shintaro; Nakashima, Mikiro; Sasaki, Hitoshi; Nakamura, Junzo 1077
2007-04 Unilateral Lung-Selective Gene Transfer Following the Administration of Naked Plasmid DNA onto the Pulmonary Pleural Surface in Mice Nakamura, Junzo; Fumoto, Shintaro; Ariyoshi, Kimiyo; Kodama, Yukinobu; Nishi, Junya; Nakashima, Mikiro; Sasaki, Hitoshi; Nishida, Koyo 890
2006-11 長崎大学医学部・歯学部附属病院における整腸剤適正使用への取り組み 江頭, かの子; 北原, 隆志; 柏木, 香; 樋口, 則英; 中嶋, 幹郎; 一川, 暢宏; 佐々木, 均 1042
2012-01-01 長崎薬学・看護学連合コンソーシアムによる地域における先導的医療人教育の展開 手嶋, 無限; 中嶋, 幹郎; 畑山, 範 539
2004-11-10 哺乳類におけるサーカディアンリズム中枢・視交叉上核の神経細胞の1細胞活動電位計測系の開発(計測) 杉尾, 嘉宏; 寺薗, 英之; 鈴木, 郁郎; 金子, 智行; 中嶋, 幹郎; 佐々木, 均; 神保, 泰彦; 安田, 賢二 278

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