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Rubusuaviins A-F, Monomeric and Oligomeric Ellagitannins from Chinese Sweet Tea and Their α-Amylase Inhibitory Activity

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Title: Rubusuaviins A-F, Monomeric and Oligomeric Ellagitannins from Chinese Sweet Tea and Their α-Amylase Inhibitory Activity
Authors: Li, Haizhou / Tanaka, Takashi / Zhang, Ying-Jun / Yang, Chong-Ren / Kouno, Isao
Issue Date: Sep-2007
Publisher: The Pharmaceutical Society of Japan
Citation: Chemical & Pharmaceutical Bulletin v.55(9) p.1325-1331, 2007
Abstract: Six new ellagitannins herein, rubusuaviins A?F, were isolated from the aqueous acetone extract of Chinese sweet tea (Tien-cha, dried leaves of Rubus suavissimus S. LEE) together with seven known tannins. Rubusuaviin A was characterized as 1-O-galloyl-2,3-O-(S)-HHDP-4,6-O-(S)-sanguisorboyl-β-D-glucopyranose. Rubusuaviins B, C, and E are dimeric, trimeric, and tetrameric ellagitannins, respectively, in which the sanguisorboyl groups were connected ellagitannin units. Rubusuaviins D and F were desgalloyl derivatives of rubusuaviins C and E, respectively. The inhibition of α-amylase activity by rubusuaviins and related ellagitannins was compared. Ellagitannins with β-galloyl groups at the glucose C-1 positions showed stronger inhibition compared with the α-galloyl and desgalloyl compounds. The molecular weight of these compounds was not important for the inhibition of α-amylase activity.
Keywords: Rubus suavissimus / Rosaceae / ellagitannin / amylase / polyphenol / tannin
URI: http://hdl.handle.net/10069/14909
ISSN: 00092363
DOI: 10.1248/cpb.55.1325
PubMed ID: 17827756
Relational Links: http://dx.doi.org/10.1248/cpb.55.1325
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/14909

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