DSpace university logo mark
Advanced Search
Japanese | English 

NAOSITE : Nagasaki University's Academic Output SITE > School of Medicine > Bulletin > Acta Medica Nagasakiensia > Volume 5, No. 1 >

Effect of Anesthetics on the Pituitary-Adrenocortical System of the Rat


File Description SizeFormat
acta05_01_06_t.pdf290.3 kBAdobe PDFView/Open

Title: Effect of Anesthetics on the Pituitary-Adrenocortical System of the Rat
Authors: Mitamura, Takaaki
Authors (alternative): 三田村, 孝朗
Issue Date: 25-Apr-1960
Citation: Acta medica Nagasakiensia. 1960, 5(1), p.58-62
Abstract: The effect of various anesthetics on the pituitary-adrenocortical system was studied in rats, using the depletion of adrenal ascorbic acid as an index of adrenal-cortical activity. The anesthetics applied were Evipan-sodium, ether, urethane, morphine and sodium pentobarbital. Anesthetization with ether, urethane and morphine (10 mg per 100 g body weight) induced a remarkable adrenal ascorbic acid depletion in rats. Ascorbic acid depletion in the adrenal after application of Evipan-sodium or morphine (2 mg per 100 g body weight) was mild, and no definite change in adrenal ascorbic acid concentration was produced by sodium pentobarbital anesthesia. In hypophysectomized rats anesthetization did not produce adrenal ascorbic acid depletion.
URI: http://hdl.handle.net/10069/15430
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 5, No. 1

Citable URI : http://hdl.handle.net/10069/15430

All items in NAOSITE are protected by copyright, with all rights reserved.

 

Valid XHTML 1.0! Copyright © 2006-2015 Nagasaki University Library - Feedback Powerd by DSpace