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Effect of Anesthetics on the Pituitary-Adrenocortical System of the Rat

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タイトル: Effect of Anesthetics on the Pituitary-Adrenocortical System of the Rat
著者: Mitamura, Takaaki
著者(別表記) : 三田村, 孝朗
発行日: 1960年 4月25日
引用: Acta medica Nagasakiensia. 1960, 5(1), p.58-62
抄録: The effect of various anesthetics on the pituitary-adrenocortical system was studied in rats, using the depletion of adrenal ascorbic acid as an index of adrenal-cortical activity. The anesthetics applied were Evipan-sodium, ether, urethane, morphine and sodium pentobarbital. Anesthetization with ether, urethane and morphine (10 mg per 100 g body weight) induced a remarkable adrenal ascorbic acid depletion in rats. Ascorbic acid depletion in the adrenal after application of Evipan-sodium or morphine (2 mg per 100 g body weight) was mild, and no definite change in adrenal ascorbic acid concentration was produced by sodium pentobarbital anesthesia. In hypophysectomized rats anesthetization did not produce adrenal ascorbic acid depletion.
URI: http://hdl.handle.net/10069/15430
ISSN: 00016055
資料タイプ: Departmental Bulletin Paper
原稿種類: publisher
出現コレクション:Volume 5, No. 1

引用URI : http://hdl.handle.net/10069/15430



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