DSpace university logo mark
Japanese | English 

NAOSITE : Nagasaki University's Academic Output SITE > 030 医学部 > 030 紀要 > Acta Medica Nagasakiensia > Volume 6, No. 1-2 >

Comparative Studies on Coronary Dilators

ファイル 記述 サイズフォーマット
acta06_01_03_t.pdf528.52 kBAdobe PDF本文ファイル

タイトル: Comparative Studies on Coronary Dilators
著者: Miyake, Nobuaki
著者(別表記) : 三宅, 信昭
発行日: 1961年 9月25日
引用: Acta medica Nagasakiensia. 1961, 6(1-2), p.13-19
抄録: The comparative potency of coronary dilators was investigated by using a rolling circular manometer system in the isolated perfused cat's heart. The doses capable of producing a 50 per cent increase in coronary blood flow were compared. The values in μM for caffeine, Diuretin, Aminophylline, hydroxyethyl-theophylline, dihydroxypropyl-theophylline, adenosine, papaverine, and Persantin were found to be 26, 28, 5, 50, 60, 0.0018, 3, and 2.5, respectively. The duration of action was evaluated by the doses required to maintain a 2-minute period of increased coronary flow. The values in μM in the same order of the compounds mentioned above were represented as 52, 28, 5, 25, 5, 0.006, 5, and 0.13, respectively. The results derived from the experiments using coronary vascular strips suggest that a possible site of action of Persantin is located in the vascular smooth muscle itself.
URI: http://hdl.handle.net/10069/15452
ISSN: 00016055
資料タイプ: Departmental Bulletin Paper
原稿種類: publisher
出現コレクション:Volume 6, No. 1-2

引用URI : http://hdl.handle.net/10069/15452



Valid XHTML 1.0! Copyright © 2006-2015 長崎大学附属図書館 - お問い合わせ Powerd by DSpace