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Adrenal Medullary Secretion in Response to Intestinal Strangulation in the Dog


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タイトル: Adrenal Medullary Secretion in Response to Intestinal Strangulation in the Dog
著者: Sugihara, Yoshiaki
著者(別表記) : 椙原, 美昭
発行日: 1971年10月25日
引用: Acta medica Nagasakiensia. 1971, 16(1-2), p.1-11
抄録: In dogs caused experimental strangulation obstruction by ligation of the upper small intestine together with the mesentery measuring 80 cm in length, adrenal venous blood was observed for the secretion rate of adrenaline and noradrenaline by the fluorimetric method. Increase of adrenal medullary secretion was not induced by the continued strangulation alone. However, when the strangulation was released three hours after the onset, the secretion rate of adrenaline and noradrenaline increased rapidly. When 250 mg of kanamycin was injected into the strangulated intestinal loop and the obstruction was released three hours later, the increase of adrenal medullary secretion was slight. When the strangulated intestinal loop was resected and anastomosed three hours after the onset of obstruction, the adrenal medullary secretion showed no increase. When strangulation was released after resection of the greater and lesser splanchnic nerves on the side wherefrom the adrenal venous blood was drawn, any increase in secretion rate of adrenaline and noradrenaline did not occur. In brief, the release of strangulation obstruction was followed by a remarkable increase of adrenal medullary secretion rate and the state of sympathetic overactivity in experimental animals. Therefore one must be careful in the administration of catecholamines at the time of intestinal obstruction and at the time of shock after release.
URI: http://hdl.handle.net/10069/15565
ISSN: 00016055
資料タイプ: Departmental Bulletin Paper
原稿種類: publisher
出現コレクション:Volume 16, No. 1-2

引用URI : http://hdl.handle.net/10069/15565

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