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Radioimmunoassay of Plasma 17α-Hydroxyprogesterone


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Title: Radioimmunoassay of Plasma 17α-Hydroxyprogesterone
Authors: Ishimaru, Tadayuki / Mori, Atsumi / Kase, Yasuaki / Miura, Seiran
Authors (alternative): 石丸, 忠之 / 森, 淳躬 / 加瀬, 泰昭 / 三浦, 清轡
Issue Date: 25-Mar-1977
Citation: Acta medica Nagasakiensia. 1976, 21(1-4), p.38-44
Abstract: A radioimmunoassay for the measurement of 17α-hydroxyprogesterone (17α-OHP) in plasma was investigated utilizing antiserum produced by the introduction of 17α-hydroxyproges- terone-3-oxim BSA. Accuracy was such that within-assay variance was 16.2% and between-assay variance 18.3%. The 17α-OHP mean plasma levels were 930±201 pg/ml(n=8)for normal adult males and 402±186 pg/ml(n=11)in the follicular phase and 1,190±662 pg/ml(n=12)in the luteal phase of females with a normal menstrual cycle. The 17α-OHP levels in some tissues and tissue fluid also were measured, being 18.06±12.91 ng/ml(n=6) in the normal trophoblastic tissue, 1.7±0.5 ng/ml(n=17) in the trophoblastic tissue of a hydatidiform mole and 855.5±507.4 ng/ml(n=5)in lutein cyst fluid.
URI: http://hdl.handle.net/10069/15589
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 21, No. 1-4

Citable URI : http://hdl.handle.net/10069/15589

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