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Clinical Value of Flow Cytometric DNA analysis in colorectal cancers


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Title: Clinical Value of Flow Cytometric DNA analysis in colorectal cancers
Authors: Tomita, Masao / Ishikawa, Hiroshi / Wakagoe, Tone / Shimizu, Teruhisa / Kusano, Hiroyoki / Takahira, Koji / Hirano, Tatsuo / Shimoyama, Takatoshi / Miura, Toshio
Issue Date: 9-Dec-1989
Citation: Acta medica Nagasakiensia. 1989, 34(2-4), p.61-64
Abstract: The distribution of DNA in colon cancers and its relationship to factors related to clinical features of cancer invasion and noncurative operation are evaluated by using paraffin-embedded specimens. The survival in patients with DNA diploid tumor is apparently much more satisfactory than that in patients with aneuploid tumor in stage B and C patients in accordance with advances in the disease stage. The deeper the depth of cancer invasion reaches, the more the number of DNA aneuploid tumor increased in the distribution. Non-curative operation was more frequently made in patients with DNA aneuploid tumor rather than in patients with DNA diploid one. In conclusion, analysis of the distribution of DNA contributes to assessment of the prognosis of colorectal carcinoma in combination with conventional prognostic parameter of clinicopathologic variables.
URI: http://hdl.handle.net/10069/15762
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 34, No. 2-4

Citable URI : http://hdl.handle.net/10069/15762

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