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Detection of Senile Plaque and Neurofibrillary Tangle using Bielschowsky-Hirano's Silver Method


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Title: Detection of Senile Plaque and Neurofibrillary Tangle using Bielschowsky-Hirano's Silver Method
Authors: Kishikawa, Masao / Iseki, Masachika / Kondo, Hisayoshi / Yoshimura, Masahiro / Fujii, Hideharu / Sekine, Ichiro
Issue Date: 9-Dec-1989
Citation: Acta medica Nagasakiensia. 1989, 34(2-4), p.65-69
Abstract: Conventional light microscopic morphometrical investigations were performed on senile plaques and neurofibrillary tangles in eighteen senile brains. Specimens from the hippocampal region were investigated statistically whether or not there is any difference in detection of senile plaques and neurofibrillary tangles among the conventional staining methods, that is, Hematoxylin-Eosin stain, Congo red stain, Periodic acid Schiff reaction, Bodian stain and Bielschowsky- Hirano's silver stain. It was clarified that, even in the laboratory without specific antibody to senile plaque and neurofibrillary tangle, Bielschowsky-Hirano's stain is the most useful and convenient staining method for detection of these ageing-related changes.
URI: http://hdl.handle.net/10069/15763
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 34, No. 2-4

Citable URI : http://hdl.handle.net/10069/15763

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