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Behavior of immunocompetent cells in the spleen and lymphnodes at lung transplantation - Especially alteration of Ia positive cell population among mononuclear cells -


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Title: Behavior of immunocompetent cells in the spleen and lymphnodes at lung transplantation - Especially alteration of Ia positive cell population among mononuclear cells -
Authors: Nakamura, Toru
Issue Date: 9-Dec-1989
Citation: Acta medica Nagasakiensia. 1989, 34(2-4), p.105-112
Abstract: The Ia-positive ratio of the immunocompetent cells in the spleen and the mesenterial lymphnodes was measured after lung transplantation on dogs treated with cyclosporin A as the immunosuppressive drug and treated without CsA. And Ia positive ratio of those cells in the peripheral blood was also measured after lung transpl-antation with and without splenectomy. At rejection, the Ia-positive ratio of lymphocytes and monocytes in the spleen was increased significantly regardless the use of CsA. And when the rejection was inhibited by CsA, Ia-positive ratio of those cells was decreased significantly. However, when the rejection was inhibited or not, the la-positive ratio of monocytes in the peripheral blood has not indicated a significant difference. Splenectomy after lung transplantation did not influenced the Ia-positive ratio of the peripheral blood immunocompetent cells.
URI: http://hdl.handle.net/10069/15770
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 34, No. 2-4

Citable URI : http://hdl.handle.net/10069/15770

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