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Nuclear DNA Analysis in Hepatocelular Carcinoma in Comparison with Clinicopathologic Factors


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Title: Nuclear DNA Analysis in Hepatocelular Carcinoma in Comparison with Clinicopathologic Factors
Authors: Tomita, Masao / Ishikawa, Hiroshi / Nakagoe, Toru / Shimizu, Teruhisa / Hirano, Tatsuo / Kunisaki, Tadaomi / Yasutake, Toru / Shimoyama, Takatoshi / Miura, Toshio
Issue Date: 14-Dec-1990
Citation: Acta medica Nagasakiensia. 1990, 35(1-4), p.92-95
Abstract: Nuclear DNA patterns were analyzed in the 33 patients with primary hepatocellular carcinoma on the basis of clinicopathologic standpoint. It is concluded that biologic behavior of hepatocellular cancer cells in patients with DNA aneuploidy pattern displayed highly malignant potential, indicating severe atypism, rapid growth of rupturing, the presence of cancer invasion into the wall of portal vein and distant metastasis. Furthermore, the survival time in patients with DNA aneuploidy pattern in hepatocellular carcinoma was shorter than that in patients with diploidy one.
URI: http://hdl.handle.net/10069/15820
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 35, No. 1-4

Citable URI : http://hdl.handle.net/10069/15820

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