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Study on Immunosuppressive Substance in Gastric Cancer


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Title: Study on Immunosuppressive Substance in Gastric Cancer
Authors: Nakao, Haruhiko
Issue Date: 14-Dec-1990
Citation: Acta medica Nagasakiensia. 1990, 35(1-4), p.259-264
Abstract: The serum immunosuppressive (IS) levels were measured in the 73 gastric cancer patients and analysed in terms of histoclinical factors of the progression of carcinoma. And also in vitro study was made to clarify the action of IS substrance on lymphocyte blastogenesis, NK and LAK cell activities. 1) The serum IS levels in gastric cancer patients increased in accordance with progression of carcinomas. It is of great benefit to assess the advancing cancer progression and to know the prognosis. 2) The serum IS levels inversely proportionated to lymphocyte blastogenesis, NK and LAK cell activities, in particular, showed close correlation with LAK cell activity. 3) In vitro study clearly indicated that IS substance inhibited lymphocyte blastogenesis, as well as NK and LAK cell activities in accordance with IS dosis-dependent manner.
URI: http://hdl.handle.net/10069/15851
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 35, No. 1-4

Citable URI : http://hdl.handle.net/10069/15851

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