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Alveolar Hemorrhage Associated with Glomerulonephritis So-called Pulmonary Renal (Goodpasture's) Syndrome


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Title: Alveolar Hemorrhage Associated with Glomerulonephritis So-called Pulmonary Renal (Goodpasture's) Syndrome
Authors: Senba, Masachika / Zhong, Xue-Yun / Itakura, Hideyo / Matsuo, Takeshi
Issue Date: 25-Dec-1993
Citation: Acta medica Nagasakiensia. 1993, 38(2-4), p.49-53
Abstract: Goodpasture's syndrome is characterized by pulmonary associated with renal abnormalities and a group of systemic diseases share immunopathogenic mechanisms which is an autoimmune antiglomerular basement membrane disease. Pulmonary renal syndrome is rather common in the western countries, but rare in Japan. The present two cases showed clinical and pathological features of rapidly progressive glomerulonephritis complicated with massive pulmonary hemorrhage. Most of the hemorrhage appeared acute with intact red blood cells in alveolar spaces, and also had variable numbers of hemosiderin-laden macrophages as an evidence of old hemorrhage. In one case of Goodpasture's syndrome, linear deposits of IgG were demonstrated in alveolar walls, glomerular capillary, Bowman's capsular basement membrane, and tubules of kidneys. These evidences indicate the present two cases to be the so-called Goodpasture's syndrome.
URI: http://hdl.handle.net/10069/15906
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 38, No. 2-4

Citable URI : http://hdl.handle.net/10069/15906

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