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Prevalence of Chronic Hepatitis B and C Virus Infection in Kami-Goto-Town, Nagasaki Prefecture, Japan.


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Title: Prevalence of Chronic Hepatitis B and C Virus Infection in Kami-Goto-Town, Nagasaki Prefecture, Japan.
Authors: Shirahama, Satoshi
Issue Date: 25-Dec-1993
Citation: Acta medica Nagasakiensia. 1993, 38(2-4), p.107-109
Abstract: Annual mass examinations in an area where the mortality rate due to liver disease is very high in Nagasaki Prefecture, Japan, have been done between 1984 and 1992 in order to evaluate the prevalence of chronic hepatitis B and C virus infection. The positivity rate for hepatitis B surface antigen (HBsAg) was 4.2%, whereas the positivity rate for anti-hepatitis C virus antibody (anti-HCV) was 9.5% as a whole and 7.2% with exclusion of the anti-HCV-positive inhabitants receiving blood transfusion. When the positivity rates for these markers were analyzed by year of birth, the positivity rate for HBsAg reached a peak (8.4%) in inhabitants born during 1941-45, and thereafter decreased. The positivity rates for anti-HCV, even when the anti-HCV-positive inhabitants receiving blood transfusion were excluded, were more than 7% in inhabitants born in 1935 and before, and thereafter followed by a decreasing trend as evidenced by the fact that none of inhabitants born in 1951 and after was anti-HCV-positive. These results suggest that the positivity rates for both of HBsAg and anti-HCV in inhabitants born in 1946 and after steadily decreace in Kami-Goto-town, where the positivity rates for these markers are, at present, very high.
URI: http://hdl.handle.net/10069/15919
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 38, No. 2-4

Citable URI : http://hdl.handle.net/10069/15919

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