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Nuclear DNA Analysis in Neuroblastoma -Significance of DNA Ploidy as a Prognostic Factor-


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Title: Nuclear DNA Analysis in Neuroblastoma -Significance of DNA Ploidy as a Prognostic Factor-
Authors: Sakai, Tsutomu
Issue Date: 25-Dec-1993
Citation: Acta medica Nagasakiensia. 1993, 38(2-4), p.144-149
Abstract: The nuclear DNA content was measured by using flow cytometer from paraffin-embedded pathological materials in neuroblastomas. In 55 neuroblastomas, diploidy pattern was found in 26 (47.6%). In contrast, aneuploidy was in 29 (52.7%). The prognosis of aneuploidy pattern is more satisfactory than that of diploidy. However, aneuploidy pattern included 62% of stage I, II, and IVs patients, 77.8% of less than the first year of age, 20% of N-myc amplification. There was unevenness of the patient's background between diploidy and aneuploidy patterns.
URI: http://hdl.handle.net/10069/15926
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 38, No. 2-4

Citable URI : http://hdl.handle.net/10069/15926

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