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A Case Report of Malignant Mullerian Mixed Tumor of the Uterus


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Title: A Case Report of Malignant Mullerian Mixed Tumor of the Uterus
Authors: Sadi, Almuktafi / Shingaki, Yoshisada / Kiyuna, Masaya / Tamamoto, Tooru / Toda, Takayoshi / Qureshi, Bilquis / Iha, Tadashi
Issue Date: 25-Oct-1994
Citation: Acta medica Nagasakiensia. 1994, 39(1-3), p.5-8
Abstract: We experienced a case of malignant Mullerian mixed tumor of the uterus of a 58-year-old female. We performed an immunohistochemical study in order to analyze the expression of various antigens in different elements of this tumor. Keratin, carcinoembryonic antigen (CEA), and epithelial membrane antigen (EMA) showed strong positive results in epithelial component, while EMA also showed positive results in some areas of sarcomatous elements. On the other hand, vimentin and S-100 gave strong positive result in non-epithelial component, but also was positive to some extent in epithelial component in this tumor. Immunohistochemical method was useful to differentiate the different components of this tumor. However, EMA, Vimentin and S-100 showed some unusual results. This discrepancy may indicate a change in the nature of tumor cells due to `microenvironmental' factors such as hormones and vita - mins. Therefore, careful evaluation is necessary to interpret the immunohistochemical results in surgical pathology.
Keywords: Malignant Mullerian mixed tumor / Uterus
URI: http://hdl.handle.net/10069/15963
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 39, No. 1-3

Citable URI : http://hdl.handle.net/10069/15963

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