DSpace university logo mark
詳細検索
Japanese | English 

NAOSITE : Nagasaki University's Academic Output SITE > 030 医学部 > 030 紀要 > Acta Medica Nagasakiensia > Volume 43, No. 1-2 >

Radiation Induced Cell Death in Cervical Squamous Cell Carcinoma : An Immunohistochemical and Ultrastructural Study


ファイル 記述 サイズフォーマット
acta43_01_07_t.pdf2.17 MBAdobe PDF本文ファイル

タイトル: Radiation Induced Cell Death in Cervical Squamous Cell Carcinoma : An Immunohistochemical and Ultrastructural Study
著者: Atari, Eio / Toda, Takayoshi / Muktafisadi, Al / Egawa, Haruhiko / Moromizat, Hidehiko / Mamadi, Touye / Kiyuna, Masaya
発行日: 1998年 6月30日
引用: Acta medica Nagasakiensia. 1998, 43(1-2), p.38-43
抄録: To study the process of cell death in cervical squamous cell carcinoma (SCC) after radiation, an ultrastructural and immunohistochemical study was performed. Paraffinembedded tissue blocks of biopsy samples pre- and postradiation stage III SCC (n = 15) were collected. Irradiation caused varying ultrastructural changes including nuclear and cytoplasmic disorganization suggesting cell necrosis. Immunohistochemically, the pre-radiation specimens showed no positive reaction for tumor necrosis factor-alpha (TNF- ホア),tumor necrosis factor-receptor(TNF-ホウ)or Fas. C-fos, p 53 and bcl-2 showed positive reactions in only a few nonirradiated specimens. All of the irradiated specimens showed a positive reaction for TNF-ホア,and variable positive reactions were observed for TNF-ホウ,Fas, p 53, c-fos and bcl-2. These results suggest that TNF-ホア,TNF-ホウ,and c-fos are responsible for radiation induced cell death in cervical SCC.
キーワード: cervical squamous cell carcinoma / cell death / TNF-alpha / TNF-receptor
URI: http://hdl.handle.net/10069/16103
ISSN: 00016055
資料タイプ: Departmental Bulletin Paper
原稿種類: publisher
出現コレクション:Volume 43, No. 1-2

引用URI : http://hdl.handle.net/10069/16103

このリポジトリに保管されている文献はすべて著作権により保護されています。
印刷やダウンロード等データの複製は、調査研究・教育または学習を目的とする場合に限定されます。

 

Valid XHTML 1.0! Copyright © 2006-2015 長崎大学附属図書館 - お問い合わせ Powerd by DSpace