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Cancer Specific Long-term Survival After Surgery for Carcinoma of the Splenic Flexure


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Title: Cancer Specific Long-term Survival After Surgery for Carcinoma of the Splenic Flexure
Authors: Nakagoe, Tohru / Sawai, Terumitsu / Tsuji, Takashi / Jibiki, Masaaki / Nanashima, Atsushi / Yamaguchi, Hiroyuki / Yasutake, Toru / Ayabe, Hiroyoshi / Ishikawa, Hiroshi
Issue Date: 15-Dec-1999
Citation: Acta medica Nagasakiensia. 1999, 44(3-4), p.45-48
Abstract: Purpose: Carcinoma of the splenic flexure is uncommon and it is associated with a high risk of obstruction. However, survival after resection of this tumor is controversial. The aim of this study was to evaluate cancer specific long-term survival after surgery for splenic flexure cancers compared to survival for the colon cancer at other sites. Patients and Methods: Of 500 patients undergoing surgery for colon cancer, 16 (3.2%) had cancers of the splenic flexure. Clinicopathological features and cancer specific longterm survival after curative resection were evaluated. Results: Splenic flexure carcinomas were found to be associated with a high risk of obstruction (4 out of 16; 25.0%) and a high risk of penetration/perforation (1 out of 16; 6.2%) compared with colon cancers at other sites (P <0.0001 and P=0.0128, respectively). Operative mortality rate for patients with carcinomas of splenic flexure was significantly higher than that of other sites (6.3% versus 0.8%; P=0.0319). However, resection for splenic flexure tumors was usually possible, and there was no difference in cancer specific long-term survival after surgery between the patients with splenic flexure cancers and the other site colon cancers (P=0.3505). Conclusions: Carcinoma of the splenic flexure has a similar prognosis to colon cancer at other sites.
Keywords: splenic flexure / colon cancers / cancer specific / long-term survival
URI: http://hdl.handle.net/10069/16145
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 44, No. 3-4

Citable URI : http://hdl.handle.net/10069/16145

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