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Juvenile Idiopathic Nonspecific Interstitial Pneumonia. and Review of Literature


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Title: Juvenile Idiopathic Nonspecific Interstitial Pneumonia. and Review of Literature
Authors: Ishii, Hiroshi / Kadota, Jun-ichi / Obata, Yoko / Kakugawa, Tomoyuki / Nagata, Towako / Kaida, Hideyuki / Mukae, Hiroshi / Kohno, Shigeru
Issue Date: 19-Dec-2001
Citation: Acta medica Nagasakiensia. 2001, 46(3-4), p.63-67
Abstract: We describe a case of juvenile idiopathic nonspecific interstitial pneumonia (NSIP). This is the first report of a Japanese patient with idiopathic NSIP aged 27 years. A computed tomographic scan of the chest showed groundglass opacities and reticular opacities in subpleural distribution. Bronchoalveolar lavage fluid revealed no specific finding except for decreased CD4/CD8 ratio of lymphocyte subset. Histopathological features on examination of thoracoscopic lung biopsy specimens were consistent with those of NSIP group III. The patient was treated with corticosteroids and immunosuppressants, but no clinical improvement was noted and the general condition has gradually worsened. Although the prognosis is generally considered to be good in patients with NSIP, some patients die as a result of progression of the disease. The prediction of prognosis based on histopathological, radiologic, and bronchoalveolar lavage cell findings in NSIP seems to be difficult at present.
Keywords: juvenile onset / idiopathic nonspecific interstitial pneumonia
URI: http://hdl.handle.net/10069/16196
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 46, No. 3-4

Citable URI : http://hdl.handle.net/10069/16196

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