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Adenomyoepithelioma of the Breast A with an Immunohistochemical Study

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Title: Adenomyoepithelioma of the Breast A with an Immunohistochemical Study
Authors: Wen, Chun, Yang / Ito, Masahiro / Nakayama, Toshiyuki / Nakashima, Masahiro / Nishimura, Toshimitsu / Hayashi, Tetsuro / Imaizumi, Toshinobu / Sekine, Ichiro
Issue Date: 19-Dec-2001
Citation: Acta medica Nagasakiensia. 2001, 46(3-4), p.73-76
Abstract: Adenomyoepithelioma is a rare primary tumor of the breast in women. It is characterized by a bicellular pattern consisting of both ductal and myoepithelial elements. We report here an additional case of adenomyoepithelioma in a 57-year-old woman. The aspiration cytology revealed atypical cell clusters, and the simple mastectomy was performed under the diagnosis of ductal carcinoma. Macroscopically, the tumor presented as a well-defined mass. Histologically, the tumor demonstrated the characteristic bicellular growth pattern consisting of ducts and a periductal proliferation of mainly polygonal neoplastic cells. Immunohistochemically, epithelial cells lining the glandular structures were strongly positive for cytokeratin and epithelial membrane antigen (EMA). Polygonal myoepithelial cells gave negative reactions with cytokeratin and EMA. Most polygonal myoepithelial cells were positive for ホア-smooth muscle actin (SMA) and S-100 protein. Our case was a representative example of a typical adenomyoepithelioma, but the cytological diagnosis needs a deep attention to avoid overdiagnosis.
Keywords: adenomyoepithelioma / breast / myoepithelial cell
URI: http://hdl.handle.net/10069/16198
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 46, No. 3-4

Citable URI : http://hdl.handle.net/10069/16198

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