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Morphometric Study of the Human Adrenocortical Adenomas (Functioning Adenomas)


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Title: Morphometric Study of the Human Adrenocortical Adenomas (Functioning Adenomas)
Authors: Irie, Junji
Issue Date: Oct-1986
Citation: Acta Medica Nagasakiensia. 1986, 31(1-4), p.76-89
Abstract: Morphometric studies on the light microscopic level were carried out on 11 cases from adrenocortical adenomas associated with primary aldosteronism (P.A.), 7 cases from those with Cushing's syndrome (C.S.) and as control, 6 cases from adrenal cortex at autopsy. Perimeter and area of cytoplasm and nuclei, form factor, nuclear contour index and nuclear cytoplasmic ratio were measured as parameters. A great variety of each parameter was characterized in the adrenocortical adenomas compared with that of control. This pleomorphism in adenoma cells may reflect an active state in steroidogenesis or a sign of active proliferation of tumor cells. Rather than compact-type cells, clear-type cells contributed to the pleomorphism of C.S.
URI: http://hdl.handle.net/10069/17476
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 31, No. 1-4

Citable URI : http://hdl.handle.net/10069/17476

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