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Oxygen Consumption in Myocardium during Experimentally-induced Aortic Stenosis


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Title: Oxygen Consumption in Myocardium during Experimentally-induced Aortic Stenosis
Authors: Igarashi, Katsuro
Issue Date: Oct-1986
Citation: Acta Medica Nagasakiensia. 1986, 31(1-4), p.322-327
Abstract: We investigated changes in oxygen consumption of the myocardium with respect to increase in subvalvular aortic stenosis, in 10 thoractomized mongrel dogs under anesthesia. A balloon catheter was advanced from the carotid artery and positioned under the aortic valve. The balloon was inflated by saline solution to produce subvalvular stenosis. Compared to pre-stenotic level the oxygen consumption remained almost unchanged at left ventricular pressure (PLV) and aortic pressure (PAo) gradient of up to 20 mmHg but showed about 15% increase at 40 mmHg and about 30% increase at 60 mmHg.. Coronary blood flow (CBF) also remained almost unchanged at pressure gradient of up to 20 mmHg but was decreased about 10% at 40 mmHg and about 20% at 60 mmHg.
Keywords: Oxygen consumption, subvalvular aortic stenosis
URI: http://hdl.handle.net/10069/17499
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 31, No. 1-4

Citable URI : http://hdl.handle.net/10069/17499

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