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Serological Evidence of Lymphocytic Choriomeningitis Virus Infection in Japan


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Title: Serological Evidence of Lymphocytic Choriomeningitis Virus Infection in Japan
Authors: Sato, Hiroshi
Issue Date: Mar-1989
Citation: Acta Medica Nagasakiensia. 1989, 34(1), p.21-23
Abstract: Indirect fluorescent antibody method was applied for a detection of lymphocytic choriomenigitis virus (LCMV) antibody in colonies of laboratory animals in Japan. The results showed that the antibody exist in SPF mice (3/152,2.0%) and conventional mice (30/539, 5.6%) with the titers ranging from 1: 10 to 1: 160. The antibody was also detected in 2.2% (2/89) of Syrian golden hamsters, and 2.9% (2/68) of Apodemus agrarius, 21.4% (3/14) of Japanese harvest mice which have been maintained as laboratory colony for several years. However, the antibody was not demonstrated in Mongolian gerbils, Suncus murius, guinea pigs and rats thus far. These results indicate that LCMV infection is present in laboratory animals in Japan, and pointed out the importance of microbiological monitoring for LCMV.
URI: http://hdl.handle.net/10069/17532
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 34, No. 1

Citable URI : http://hdl.handle.net/10069/17532

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