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A Case Report of Renal Cell Carcinoma Producing Alpha-Fetoprotein


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Title: A Case Report of Renal Cell Carcinoma Producing Alpha-Fetoprotein
Authors: Shimajiri, Shouhei / Shingaki, Yoshisada / Sasi, Ai Muktafi / Kiyuna, Masaya / Tamamoto, Tooru / Toda, Takayoshi / Hayakawa, Masamichi
Issue Date: 25-Dec-1992
Citation: Acta Medica Nagasakiensia. 1992, 37(1-4), p.78-81
Abstract: We report a rare autopsy case of alpha-fetoprotein producing renal cell carcinoma with multiple metastases to liver, gallbladder, mesenterium, and paraaortic lymphnodes. A 58-year-old male patient was diagnosed as having carcinoma of the right kidney. On admission, the patient showed increased serum level of alphafetoprotein (326 ng/ml) which decreased after resection of the renal tumor. The resected tumor was composed mainly of clear cell type of carcinoma cells and partially of granular cells. At autopsy, the main cell type of the metastatic foci was granular type of carcinoma cells. Immunohistochemistry of alpha-fetoprotein by PAP method revealed more positive reaction on granular cell type of carcinoma cells than clear cell type of carcinoma cells in the primary site of the kidney as well as in the metastatic foci.
Keywords: alpha-fetoprotein, granular cell type, renal cell carcinoma.
URI: http://hdl.handle.net/10069/17561
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 37, No. 1-4

Citable URI : http://hdl.handle.net/10069/17561

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