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糖尿病初回治療例における患者像および初期治療効果


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Title: 糖尿病初回治療例における患者像および初期治療効果
Other Titles: Clinical feastures and effects of initial treatment of the patients with diabetes mellitus
Authors: 大塚, 健作 / 河本, 令子 / 西山, 久美子 / 江藤, 宏美
Authors (alternative): Otsuka, Kensaku / Kawamoto, Reiko / Nishiyama, Kumiko / Eto, Hiromi
Issue Date: 31-Mar-1990
Citation: 長崎大学医療技術短期大学部紀要 = Bulletin of the School of Allied Medical Sciences, Nagasaki University. 1990, 3, p.45-52
Abstract: 糖尿病初回治療患者148例において,治療開始までの期間,網膜症の頻度,初期治療効果などにつき検討した.発見時自覚症状の有無と治療開始までの期間をみると,症状が無い例の約60%は1年以上放置しており,症状ある群の15%に比し多く,また網膜症の頻度も有意に高かった.初診時における網膜症の頻度は26.0%であったが,早期受診群で15.3%,1年以上放置群41.5%(5年以上放置群では57.9%)となり,放置群では有意に高頻度だった.また治療中断者が19例あり,うち18例は自覚症状がなく,その有無は治療の動機づけに大きな影響を与えると考えられる.初期治療の効果を治療開始後2ケ月以内のFPGでみると,全例で明らかな低下がみられ,およそ80%の例で120㎎/dl以下になった. / The clinical features, patient profiles and the effects of the first trial treatment were studied for 148 cases of patients with diabeties, in which the levels of fasting plasma glucose (FPG) were 120 mg/dl or more before treatment. The patients were divided into the several groups acording to the duration of the untreated periods or the presence of symptoms when diabetes was diagnosed. The prevalence rate for diabetic retinopathy (DR) was 26.0% in all the subjects at the first vsit for treatment. Patients without symptoms tended to have put off treatment for a long priod, and their prevalence rates for DR were significantly higher than those of patients who visited within a year of diagnosis. Nineteen patients discontinued hospital visits befofe treatment was started, and 18 of them were in the group without symtoms. This suggests that presence of symptoms affects the patient's motivation for trearment. The effects of the initial treatment were evaluated based on the lowest FPG obtained within two months of starting treatment. The initial selected types of treatment and numbers of patients were diet omly (48), biguanide (4), sulfonylurea (33), insulin (32) and diet control shortly after drug therapy (12). All the forms of treatment lowered the FPG and resulted in levels of less than 120 mg/dl in approximately 80% of the cases.
Keywords: 初回治療 / 治療法の選択 / 網膜症の頻度 / 初期治療効果 / 放置期間
URI: http://hdl.handle.net/10069/18117
ISSN: 09160841
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 3

Citable URI : http://hdl.handle.net/10069/18117

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