DSpace university logo mark
Advanced Search
Japanese | English 

NAOSITE : Nagasaki University's Academic Output SITE > School of Pharmaceutical Sciences > Articles in academic journal >


File Description SizeFormat
Yakugaku128_1119.pdf1.44 MBAdobe PDFView/Open

Title: 植物ポリフェノールに関する化学的研究とその紅茶色素生成機構解明への展開
Other Titles: Chemical Studies on Plant Polyphenols and Formation of Black Tea Polyphenols
Authors: 田中, 隆
Authors (alternative): Tanaka, Takashi
Issue Date: Aug-2008
Publisher: 日本薬学会
Citation: 藥學雜誌, 128(8), pp.1119-1131; 2008
Abstract: Recent biological and pharmacological studies strongly suggested that plant polyphenols in foods, beverages and crude drugs have various health benefits. However, still there are chemically uncharacterized polyphenols, especially those with large molecular weights. The typical example is black tea polyphenols. Four tea catechins of fresh tea leaves are enzymatically oxidized in tea fermentation process of black tea manufacture to give a complex mixture of the oxidation products. Despite many efforts since 1950's, major part of the black tea polyphenols has not been clarified yet. We have investigated the oxidation mechanism of each catechin by employing a newly developed in vitro model fermentation system. The oxidation was initiated by enzymatic dehydrogenation of catechins, and subsequent intermolecular quinone-phenol coupling reactions followed by cascade-type degradation of the unstable products resulted in the formation of complex black tea polyphenols. Besides black tea polyphenols, this review introduces the chemistry of insolubilization of persimmon proanthocyanidins, wood polyphenols in connection with whisky polyphenols, and co-polymerization of cinnamaldehyde and proanthocyanidins in cinnamon bark.
Description: 平成19年度宮田記念学術論文賞受賞記念総説
Keywords: Black tea / Catechin / Polyphenol / Proanthocyanidin / Tannin
URI: http://hdl.handle.net/10069/19204
ISSN: 00316903
DOI: 10.1248/yakushi.128.1119
PubMed ID: 18670177
Rights: Copyright (c) 2008 by the PHARMACEUTICAL SOCIETY OF JAPAN
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/19204

All items in NAOSITE are protected by copyright, with all rights reserved.


Valid XHTML 1.0! Copyright © 2006-2015 Nagasaki University Library - Feedback Powerd by DSpace