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Successful cord blood transplantation for mycosis fungoides.

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Title: Successful cord blood transplantation for mycosis fungoides.
Authors: Fukushima, Takuya / Horio, Kensuke / Matsuo, Emi / Imanishi, Daisuke / Yamasaki, Reishi / Tsushima, Hideki / Imaizumi, Yoshitaka / Ohshima, Koichi / Hata, Tomoko / Yoshida, Shinichiro / Miyazaki, Yasushi / Tomonaga, Masao
Issue Date: 1-Dec-2008
Publisher: Japanese Society of Hematology
Citation: International Journal of Hematology, 88(5), pp. 596-598; 2008
Abstract: A 26-year-old female diagnosed as mycosis fungoides (MF, clinical stage IV) was treated with single-agent chemotherapy, multi-drug chemotherapy and unrelated bone marrow transplantation with reduced-intensity conditioning (engraftment failure), resulting in failure. Unrelated cord blood transplantation (CBT) as second transplantation following myeloablative conditioning brought complete remission (CR), but relapse of MF occurred 3 months after transplantation. However, discontinuation of immune suppressant led to the regression of MF regions and to second CR that continued for more than 23 months. This is the first report of successful CBT for MF, suggesting the graft-versus-MF effect in a setting of CBT.
Description: The original publication is available at www.springerlink.com
Keywords: Mycosis fungoides / Cord blood transplantation / Graft-versus-lymphoma effect
URI: http://hdl.handle.net/10069/21872
ISSN: 18653774
DOI: 10.1007/s12185-008-0190-4
PubMed ID: 18998050
Rights: (c)2008 Japanese Society of Hematology
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/21872

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