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A Case of Pseudoangiomatous Stromal Hyperplasia of the Breast Presenting with Chest Pain

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Title: A Case of Pseudoangiomatous Stromal Hyperplasia of the Breast Presenting with Chest Pain
Authors: Amenomori, Misato / Hayashi, Tomayoshi / Abe, Kuniko / Itoyanagi, Noriaki / Kohno, Shigeru
Issue Date: 27-Jan-2009
Publisher: Bentham Open
Citation: The Open Breast Cancer Journal, 1(1), pp. 10-13; 2009
Abstract: Pseudoangiomatous stromal hyperplasia is a rare, benign, breast disease characterized by dense, collagenous proliferation of mammary stroma, forming interanastomosing capillary-like spaces. Previously reported cases presented with a palpable breast mass or continuous breast enlargement, or were unexpectedly detected on mammography or ultrasonography. However, cases presenting only with pain as the initial symptom have not been reported. In this report, we describe a case of pseudoangiomatous stromal hyperplasia that presented with intermittent dull chest pain. A 2.6 x 1.1 cm, well-defined, hypoechoic mass was noted in the breast on ultrasonography, and an excisional biopsy was performed. On pathology, the tumor showed stromal hyperplasia and vessel-like slit structures. Immunohistochemical staining for vimentin, CD34, CD31, and Factor VIII-related antigen was compatible with pseudoangiomatous stromal hyperplasia. The dull chest pain disappeared after the excision. Pseudoangiomatous stromal hyperplasia is often described as painless. However, chest pain could also be an initial symptom.
Keywords: Pseudoangiomatous stromal hyperplasia (PASH) / chest pain / benign breast tumor
URI: http://hdl.handle.net/10069/21931
ISSN: 18768172
DOI: 10.2174/1876817200901010010
Rights: © Amenomori et al.; Licensee Bentham Open. This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/ 3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/21931

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