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Isoniazid-triggered pure red cell aplasia in systemic lupus erythematosus complicated with myasthenia gravis.


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Title: Isoniazid-triggered pure red cell aplasia in systemic lupus erythematosus complicated with myasthenia gravis.
Authors: Nakamura, Hideki / Okada, Akitomo / Kawakami, Atsushi / Yamasaki, Satoshi / Ida, Hiroaki / Motomura, Masakatsu / Imanishi, Daisuke / Eguchi, Katsumi
Issue Date: Nov-2010
Publisher: Springer Berlin
Citation: Rheumatology international, 30(12), pp.1643-1645; 2010
Abstract: A 47-year-old woman who had been treated for systemic lupus erythematosus (SLE) with myasthenia gravis (MG) was admitted to our hospital with acute onset of severe anemia after administration of isoniazid. Pure red cell aplasia (PRCA) was confirmed by elevated serum iron levels, reticulocytopenia and bone marrow aspiration showing a remarkable reduction of erythroblasts. Finally, cyclosporine A successfully improved PRCA. Although both SLE and MG have the potential complication of PRCA, we report here a case of isoniazid-triggered PRCA.
Keywords: Pure red cell aplasia / Isoniazid / Systemic lupus erythematosus / Myasthenia gravis / Cyclosporine A
URI: http://hdl.handle.net/10069/22254
ISSN: 01728172
DOI: 10.1007/s00296-009-1113-2
PubMed ID: 19705120
Rights: © 2009 Springer-Verlag. / The original publication is available at www.springerlink.com
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/22254

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