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A case of mixed connective tissue disease complicated with hypertrophic obstructive cardiomyopathy.

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Title: A case of mixed connective tissue disease complicated with hypertrophic obstructive cardiomyopathy.
Authors: Nakamura, Hideki / Tateishi, Seiko / Kawakami, Atsushi / Ida, Hiroaki / Fukuda, Taku / Sasaki, Michiyo / Koide, Yuji / Ashizawa, Naoto / Seto, Shinji / Hayashi, Tomayoshi / Sato, Shinichi / Eguchi, Katsumi
Issue Date: Oct-2008
Publisher: Springer Berlin
Citation: Rheumatology international, 28(12), pp.1273-1275; 2008
Abstract: A 54-year-old female was diagnosed as mixed connective tissue disease (MCTD) complicated with secondary Sjögren's syndrome. Although she had no dyspnea on exertion, the chest X-ray showed cardiomegaly with interstitial pneumonia. The echocardiogram demonstrated asymmetric hypertrophy of the interventricular septum. Diagnosis of hypertrophic obstructive cardiomyopathy (HOCM) was confirmed by left ventriculography and myocardial biopsy. She was treated with prednisolone, resulting in improvement of swollen hand, elevated muscle enzymes and interstitial pneumonia. A rare complication of HOCM with MCTD was described.
Keywords: HLA-DR4 / Hypertrophic obstructive cardiomyopathy / Mixed connective tissue disease
URI: http://hdl.handle.net/10069/22524
ISSN: 01728172
DOI: 10.1007/s00296-008-0608-6
PubMed ID: 18493766
Rights: © Springer-Verlag 2008 / The original publication is available at www.springerlink.com
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/22524

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