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Nonalcoholic Steatohepatitis with Improved Hepatic Fibrosis after Weight Reduction


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Title: Nonalcoholic Steatohepatitis with Improved Hepatic Fibrosis after Weight Reduction
Authors: Fujikawa, Keita / Ohata, Kazuyuki / Honda, Takuya / Miyazoe, Seiji / Ichikawa, Tatsuki / Ishikawa, Hiroki / Hamasaki, Keisuke / Nakao, Kazuhiko / Toriyama, Kan / Eguchi, Katsumi
Issue Date: Apr-2004
Publisher: 日本内科学会 / The Japanese Society of Internal Medicine
Citation: Internal Medicine, vol.43(4), pp.289-294; 2004
Abstract: A 65-year-old woman was admitted to our hospital for an investigation of liver dysfunction. She had mild obesity with hyperlipidemia, but no history of alcohol abuse. Other known causes of liver dysfunction, such as viruses, autoimmunity and drug effects, were excluded. The liver histology was consistent with nonalcoholic steatohepatitis (NASH). After diagnosis of NASH, the patient started diet and exercise therapy and, in parallel with weight reduction, her liver function improved. One year after the therapy, a liver biopsy showed that steatosis, necroinflammation and even fibrosis were improved. Hence, here we report a case of NASH in which weight reduction was effective in improving both biochemical and histological findings.
Keywords: nonalcoholic steatohepatitis / weight reduction / hepatic fibrosis
URI: http://hdl.handle.net/10069/22541
ISSN: 09182918
DOI: 10.2169/internalmedicine.43.289
Rights: Copyright (c) 2005 (社)日本内科学会
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/22541

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