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Hepatitis B Related Polyarteritis Nodosa Presenting Necrotizing Vasculitis in the Hepatobiliary System Successfully Treated with Lamivudine, Plasmapheresis and Glucocorticoid


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Title: Hepatitis B Related Polyarteritis Nodosa Presenting Necrotizing Vasculitis in the Hepatobiliary System Successfully Treated with Lamivudine, Plasmapheresis and Glucocorticoid
Authors: Takeshita, Shigeyuki / Nakamura, Hideki / Kawakami, Atsushi / Fukushima, Tetsuya / Gotoh, Takashi / Ichikawa, Tatsuki / Tsujino, Akira / Ida, Hiroaki / Toriyama, Kan / Hayashi, Tomayoshi / Eguchi, Katsumi
Issue Date: Mar-2006
Publisher: 日本内科学会 / The Japanese Society of Internal Medicine
Citation: Internal Medicine, vol.45(3), pp.145-149; 2006
Abstract: A 64yearold man was admitted for alithiasic cholecystitis. Necrotizing vasculitis was detected in a gallbladder obtained at the cholecystectomy. Slight elevation of transaminases, HBe antigens and hepatitis BDNA (HBVDNA) were detected in the patient. Intrahepatic necrotizing vasculitis was also detected in the liver biopsy specimen, and he also suffered from peripheral neuropathy of suddenly onset. Based on the diagnosis of hepatitis Brelated polyarteritis nodosa, lamivudine was initially administered, followed by plasmapheresis and glucocorticoid steroid therapy. These treatments brought satisfactory improvement of polyarteritis nodosa without exacerbation of liver function.
Keywords: Hepatitis B / polyarteritis nodosa / alithiasic cholecystitis / lamivudine / plasmapheresis / glucocorticoid therapy
URI: http://hdl.handle.net/10069/22553
ISSN: 09182918
DOI: 10.2169/internalmedicine.45.1460
Rights: Copyright (c) 2006 (社)日本内科学会
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/22553

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