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The Bactericidal Efficacy of a Photocatalytic TiO2 Particle Mixture with Oxidizer against Staphylococcus aureus


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Title: The Bactericidal Efficacy of a Photocatalytic TiO2 Particle Mixture with Oxidizer against Staphylococcus aureus
Authors: Asahara, Tomohiko / Koseki, Hironobu / Tsurumoto, Toshiyuki / Shiraishi, Koutaro / Shindo, Hiroyuki / Baba, Koumei / Taoda, Hiroshi / Terasaki, Nao
Issue Date: Sep-2009
Publisher: National Institute of Infectious Diseases / 国立感染症研究所
Citation: Japanese Journal of Infectious Diseases, 62(5), pp. 378-380; 2009
Abstract: By proving the bactericidal effects of a low-concentration titanium dioxide (TiO2) particle mixture against Staphylococcus aureus, we hope to ultimately apply a mixture of this type as part of a clinical treatment regimen. A bacterial suspension of S. aureus 1×105 CFU/ml was added dropwise to a TiO2 particle mixture (19 ppm TiO2) and irradiated by ultraviolet (UV) light. The colony-forming units were counted and the bacterial survival rate was calculated. In the control sample, the bacterial survival rate was 83.3% even after 120 min. In the TiO2 mixture + UV sample, the bacteria count dropped sharply, reaching 17.3% of the baseline value at 30 min and 0.4% at 60 min. TiO2 particles dispersed in water mixtures are known to elicit highly efficient UV absorption and greater bonding to bacteria. A reaction of the TiO2 with another oxidizer altered the aqueous pH and accelerated the photocatalytic chemical reaction. The TiO2 particle mixture showed high antibacterial action against S. aureus even at a low concentration.
URI: http://hdl.handle.net/10069/22637
ISSN: 13446304
PubMed ID: 19762988
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/22637

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