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Multiple Immune Abnormalities in a Patient with Idiopathic CD4+ T-Lymphocytopenia

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タイトル: Multiple Immune Abnormalities in a Patient with Idiopathic CD4+ T-Lymphocytopenia
著者: Yamada, Yasuaki / Okada, Masahiko / Kamitamari, Akira / Moriuchi, Hiroyuki / Yanai, Masanori / Hano, Osamu / Tsukasaki, Kunihiro / Tsuruda, Kazuto / Hasegawa, Hiroo / Yanagihara, Katsunori / Kamihira, Shimeru
発行日: 2009年
出版者: Japanese Society of Internal Medicine / 日本内科学会
引用: Internal Medicine, 48(22), pp.1967-1971; 2009
抄録: Idiopathic CD4+ T-lymphocytopenia (ICL) is a new disease entity characterized by CD4+ T-lymphocyte depletion without evidence of HIV infection. We report a 27-year-old ICL patient with a long history of multiple immune abnormalities. His CD4+ T-lymphocyte count started to decrease after generalized lymphadenopathy of an unknown cause at age 3. He satisfied the criteria for ICL at age 9, and the decreased CD4+ Tlymphocyte count persisted for more than 18 years. This is probably the first childhood-onset ICL case in which the trigger event for the development was known together with the patient's autoimmune background.
キーワード: CD4 / ICL / T lymphocytopenia
URI: http://hdl.handle.net/10069/22663
ISSN: 09182918
DOI: 10.2169/internalmedicine.48.2623
権利: © 2009 The Japanese Society of Internal Medicine.
資料タイプ: Journal Article
原稿種類: publisher
出現コレクション:130 学術雑誌論文

引用URI : http://hdl.handle.net/10069/22663



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