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Intracranial internal carotid artery stenosis with vulnerable plaques successfully treated by stenting under cerebral protection.


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Title: Intracranial internal carotid artery stenosis with vulnerable plaques successfully treated by stenting under cerebral protection.
Authors: Hiu, Takeshi / Hayashi, Kentaro / Kitagawa, Naoki / Tsutsumi, Keisuke / Horie, Nobutaka / Morikawa, Minoru / Honda, Masaru / Suyama, Kazuhiko / Nagata, Izumi
Issue Date: Dec-2008
Publisher: Elsevier B.V.
Citation: Clinical neurology and neurosurgery, 110(10), pp.1031-1034; 2008
Abstract: Percutaneous transluminal angioplasty with stenting (PTA/stenting) for intracranial atherosclerotic stenoses is usually performed without any protection devices. We report a unique case of atherothrombotic stenosis with the vulnerable plaque in the cavernous portion of the internal carotid artery (ICA), which was successfully treated by PTA/stenting under cerebral protection with the flow reversal system. A 68-year-old woman presented repetitive transient ischemic attacks in the right ICA territory. Cerebral angiography revealed 80% stenosis in the cavernous portion of the right ICA. High-resolution magnetic resonance imaging (HR-MRI) demonstrated lipid-rich plaques at this lesion. PTA/stenting was performed with a proximal protection device under flow reversal. A filter device captured much amount of atherothrombotic debris with lipid-rich macrophages and leukocytes, which was consistent with HR-MRI findings. Some selected cases of intracranial atherothrombotic ICA stenoses may need endovascular treatment with cerebral protection system. HR-MRI is useful to evaluate plaque characteristics even in the cavernous portion of the ICA.
Keywords: Cerebral protection / Flow reversal system / High-resolution magnetic resonance imaging / Intracranial internal carotid artery / Stenosis / Stenting
URI: http://hdl.handle.net/10069/23081
ISSN: 03038467
DOI: 10.1016/j.clineuro.2008.06.018
PubMed ID: 18722708
Rights: Copyright © 2008 Elsevier B.V. All rights reserved.
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/23081

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