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Drug-induced Eosinophilic Pneumonia with Pulmonary Alveolar Hemorrhage Caused by Benzbromarone


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Title: Drug-induced Eosinophilic Pneumonia with Pulmonary Alveolar Hemorrhage Caused by Benzbromarone
Authors: Hara, Atsuko / Mukae, Hiroshi / Hara, Shintaro / Amenomori, Misato / Ishimoto, Hiroshi / Kakugawa, Tomoyuki / Fujita, Hanako / Sakamoto, Noriho / Ishii, Hiroshi / Ishimatsu, Yuji / Kohno, Shigeru
Issue Date: 2010
Publisher: The Japanese Society of Internal Medicine / 日本内科学会
Citation: Internal Medicine, 49(5), pp.435-438; 2010
Abstract: A 51-year-old man was admitted to our hospital with cough, hemosputum, dyspnea and chest pain. Chest high-resolution computed tomography (HRCT) revealed diffuse ground-glass opacities in both lungs with peripheral predominance. Bronchoalveolar lavage fluid was fresh-bloody and analysis indicated an increase in the eosinophil proportion. Benzbromarone-induced lymphocyte stimulation test was positive. Therefore, the patient was diagnosed as having drug-induced eosinophilic pneumonia with pulmonary alveolar hemorrhage caused by benzbromarone. After discontinuation of benzbromarone and administration of corticosteroids, chest HRCT images and respiratory manifestation improved. Here, we report this rare case of benzbromarone-induced eosinophilic pneumonia with pulmonary alveolar hemorrhage.
Keywords: Benzbromarone / Drug-induced eosinophilic pneumonia / Pulmonary alveolar hemorrhage
URI: http://hdl.handle.net/10069/23110
ISSN: 09182918
DOI: 10.2169/internalmedicine.49.2830
Rights: © 2010 The Japanese Society of Internal Medicine.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/23110

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