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Significance of the T2*-weighted gradient echo brain imaging in patients with infective endocarditis.


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Title: Significance of the T2*-weighted gradient echo brain imaging in patients with infective endocarditis.
Authors: Morofuji, Yoichi / Morikawa, Minoru / Yohei, Tateishi / Kitagawa, Naoki / Hayashi, Kentaro / Takeshita, Tomonori / Suyama, Kazuhiko / Nagata, Izumi
Issue Date: 2-Apr-2010
Publisher: Elsevier B.V.
Citation: Clinical neurology and neurosurgery, 112(5), pp.436-440; 2010
Abstract: BACKGROUND: Although aneurysm formation accompanying parenchymal hemorrhage is one of devastating complications in the central nerves system (CNS), imaging studies of the brain are not routinely warranted in patients with infective endocarditis (IE). To assess the clinical importance for detecting silent lesions in the central nervous system, we investigated hypointense signal spots detected on the brain T2*-weighted MR imaging in patients with IE. METHODS AND RESULTS: Eleven patients with IE were retrospectively reviewed. Seven patients (63.6%) showed hypointense signal spots on T2*-weighted MR images. The number of hypointense signal spots increased within only a few weeks in five patients. CONCLUSION: The brain T2*-weighted MR imaging in patients with IE may have a potential role to detect CNS lesions with clinical significance of potentially high risk of intracranial hemorrhage. T2*-weighted hypointense signal spots may be specific to brain involvement, and be quite useful in monitoring CNS lesions associated with IE, even if they are asymptomatic.
Keywords: Infective endocarditis / Intracranial infectious aneurysm / T2*-weighted magnetic resonance imaging
URI: http://hdl.handle.net/10069/23141
ISSN: 03038467
DOI: 10.1016/j.clineuro.2010.03.004
PubMed ID: 20363553
Rights: Copyright © 2010 Elsevier B.V. All rights reserved.
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/23141

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