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Escherichia coli contamination of menstrual blood and effect of bacterial endotoxin on endometriosis


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Title: Escherichia coli contamination of menstrual blood and effect of bacterial endotoxin on endometriosis
Authors: Khan, Khaleque Newaz / Kitajima, Michio / Hiraki, Koichi / Yamaguchi, Naohiro / Katamine, Shigeru / Matsuyama, Toshifumi / Nakashima, Masahiro / Fujishita, Akira / Ishimaru, Tadayuki / Masuzaki, Hideaki
Issue Date: Dec-2010
Publisher: Elsevier Inc.
Citation: Fertility and Sterility, 94(7), pp.2860-2863; 2010
Abstract: To test the hypothesis that bacterial contamination of menstrual blood could be a local biologic event in the development of endometriosis, menstrual blood was cultured and bacterial endotoxin was measured in menstrual blood and peritoneal fluid. Our results suggest that compared with control women, higher colony formation of Escherichia coli in menstrual blood and endotoxin levels in menstrual fluid and peritoneal fluid in women with endometriosis may promote Toll-like receptor 4-mediated growth of endometriosis.
Keywords: cell growth / Endometriosis / Escherichia coli / macrophages / menstrual blood / peritoneal fluid / TLR4
URI: http://hdl.handle.net/10069/23262
ISSN: 00150282
DOI: 10.1016/j.fertnstert.2010.04.053
Rights: Copyright © 2010 American Society for Reproductive Medicine Published by Elsevier Inc.
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/23262

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