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Lingual metastasis as an initial presentation of renal cell carcinoma.


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Title: Lingual metastasis as an initial presentation of renal cell carcinoma.
Authors: Yoshitomi, Izumi / Kawasaki, Goro / Mizuno, Akio / Nishikido, Masaharu / Hayashi, Tomayoshi / Fujita, Shuichi / Ikeda, Tohru
Issue Date: Dec-2011
Publisher: Humana Press Inc.
Citation: Medical oncology, 28(4), pp.1389-1394; 2011
Abstract: Distant metastasis of malignant neoplasm to the oral soft tissue is extremely rare. We report a case of renal cell carcinoma (RCC) metastasizing to the tongue. A 47-year-old man visited our hospital with chief complaint of a lump on the middle third of the dorsum of his tongue and the lesion fell off from the tongue. Although histopathological diagnosis of the mass was granuloma teleangiectaticum, similar nodule reappeared in the same area 2 weeks later. The second lesion was composed of granuloma teleangiectaticum and aggregation of neoplastic clear cells in ductal arrangement. The clear cells were immunohistochemically positive for EMA and CD10. The abdominal CT scan revealed a 5.5 cm mass in the left kidney, suggesting RCC. Thus, the lingual lesion was consistent with metastatic RCC. There has been no recurrence for 2 years after the radical nephrectomy and local excision of the tongue.
Description: The original publication is available at www.springerlink.com
Keywords: CD10 / Lingual metastasis / Renal cell carcinoma
URI: http://hdl.handle.net/10069/23342
ISSN: 13570560
DOI: 10.1007/s12032-010-9596-y
PubMed ID: 20567942
Rights: © Springer Science+Business Media, LLC 2010
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/23342

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