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Salivary gland ultrasonography: can it be an alternative to sialography as an imaging modality for Sjogren's syndrome?

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タイトル: Salivary gland ultrasonography: can it be an alternative to sialography as an imaging modality for Sjogren's syndrome?
著者: Takagi, Yukinori / Kimura, Yasuo / Nakamura, Hideki / Sasaki, Miho / Eguchi, Katsumi / Nakamura, Takashi
発行日: 2010年 7月
出版者: BMJ Publishing Group
引用: Annals of the rheumatic diseases, 69(7), pp.1321-1324; 2010
抄録: OBJECTIVES: Salivary ultrasonography (US) was evaluated as an alternative imaging modality to sialography for Sjögren's syndrome (SS). METHODS: Parotid sialography and parotid and submandibular US were performed in 360 patients (188 with SS and 172 non-SS) who were suspected of SS and had fulfilled the American-European criteria (AEC) for SS or had received > or =3 of the objective examinations that were considered minimal requirements for classifying non-SS and had undergone both the imaging examinations. The glands were considered positive for SS if they exhibited peripheral sialoectatic changes on sialography and/or hypoechoic areas, echogenic streaks and/or irregular gland margins on US. The images obtained were independently rated as SS-positive or SS-negative by three radiologists in a blind fashion and the final decision was made by consensus. Interobserver and intermodality agreement was evaluated using kappa values for sialography and parotid and/or submandibular US. RESULTS: Average kappa values for the interobserver agreement were 0.81, 0.80 and 0.82 in sialography, parotid and submandibular US, respectively, indicating very good or good agreement. The kappa value for intermodality agreement between sialography and parotid US was 0.81 and between sialography and submandibular US was 0.76, indicating very good and good agreement, respectively. The diagnostic ability of parotid US was significantly lower than that of sialography (p<0.001, McNemar test). However, the diagnostic ability of submandibular US was comparable to that of sialography (p=0.153). CONCLUSIONS: Submandibular US is a promising technique that can be used as a practical alternative to sialography in the classification of SS.
URI: http://hdl.handle.net/10069/23874
ISSN: 00034967
DOI: 10.1136/ard.2009.123836
PubMed ID: 20498211
資料タイプ: Journal Article
原稿種類: publisher
出現コレクション:040 学術雑誌論文

引用URI : http://hdl.handle.net/10069/23874



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