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Macrophage-dominant sialadenitis in human T-cell leukemia virus type I-associated myelopathy after living-donor liver transplantation.


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Title: Macrophage-dominant sialadenitis in human T-cell leukemia virus type I-associated myelopathy after living-donor liver transplantation.
Authors: Nakamura, Hideki / Ichikawa, Tatsuki / Nakamura, Tatsufumi / Kawakami, Atsushi / Iwamoto, Naoki / Matsuzaki, Toshihisa / Miyaaki, Hisamitsu / Yamasaki, Satoshi / Ida, Hiroaki / Eguchi, Susumu / Hayashi, Tomayoshi / Nakao, Kazuhiko / Kanematsu, Takashi / Eguchi, Katsumi
Issue Date: Sep-2010
Publisher: Elsevier Inc.
Citation: Transplantation proceedings, 42(7), pp.2797-2799; 2010
Abstract: A 64-year-old man who suffered from human T-cell leukemia virus type I (HTLV-I)-associated myelopathy (HAM) after living-donor liver transplantation (LDLT) for liver cirrhosis due to hepatitis C virus infection complained of xerostomia. Although exocrine function test results were positive, autoantibodies including anti-SS-A/SS-B antibodies and sialography showed negative findings. Labial salivary gland biopsy revealing infiltration of 60 counts of mononuclear cells (MNCs) in minor salivary glands led to a diagnosis of Sjögren's syndrome-like sialadenitis. Immunohistochemistry demonstrated dominant CD68 staining and major histocompatibility complex class II on the surface of infiltrating MNCs. Herein we have reported a rare condition of macrophage-dominant sialadenitis in a patient with HAM after LDLT.
Keywords: Sialadenitis / HTLV-I infection / hepatitis C virus / Sjögren’s syndrome / Macrophage
URI: http://hdl.handle.net/10069/24109
ISSN: 00411345
DOI: 10.1016/j.transproceed.2010.04.050
PubMed ID: 20832591
Rights: Copyright © 2010 Elsevier Inc. All rights reserved.
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/24109

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