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Importance of Controlling Drug-resistant Pseudomonas aeruginosa Infection: Experience from Lung Transplantation in a Cystic Fibrosis Case


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Title: Importance of Controlling Drug-resistant Pseudomonas aeruginosa Infection: Experience from Lung Transplantation in a Cystic Fibrosis Case
Authors: Yamamoto, Yoshihiro / Izumikawa, Koichi / Hara, Atsuko / Fujita, Hanako / Amenomori, Misato / Sakamoto, Noriho / Seki, Masafumi / Kakeya, Hiroshi / Yanagihara, Katsunori / Takasaki, Kenji / Miyazaki, Takuro / Tsuchiya, Tomoshi / Yamasaki, Naoya / Tagawa, Tsutomu / Nagayasu, Takeshi / Kohno, Shigeru
Issue Date: 2010
Publisher: The Japanese Society of Internal Medicine / 日本内科学会
Citation: Internal Medicine, 49(21), pp.2353-2358; 2010
Abstract: Cystic fibrosis (CF) is rare in Japan. We encountered a CF case with drug-resistant Pseudomonas aeruginosa infection and successfully performed lung transplant from living related donors. A combination of betalactams and aminoglycosides for drug-resistant P. aeruginosa infection was administered before lung transplantation. Intravenous colistin was also used immediately before and after transplant surgery. Gram staining of respiratory specimens was performed every day after surgery and it was useful in monitoring infection status. Strict monitoring of infections by the Gram staining and culture of respiratory specimens is considered to be effective in preventing lower respiratory infection in lung transplantation.
Keywords: Cystic fibrosis / Lung transplantation / Pseudomonas aeruginosa / Ventilator-associated tracheobronchitis
URI: http://hdl.handle.net/10069/24562
ISSN: 09182918
DOI: 10.2169/internalmedicine.49.3932
Rights: Copyright (c) 2010 by The Japanese Society of Internal Medicine
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/24562

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