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New Diketopiperazine Derivatives Isolated from Sea Urchin-Derived Bacillus sp.


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Title: New Diketopiperazine Derivatives Isolated from Sea Urchin-Derived Bacillus sp.
Authors: Yonezawa, Ken / Yamada, Koji / Kouno, Isao
Issue Date: Jan-2011
Publisher: The Pharmaceutical Society of Japan / 日本薬学会
Citation: CHEMICAL & PHARMACEUTICAL BULLETIN, 59(1), pp.106-108; 2011
Abstract: Two new diketopiperazine derivatives, bacillusamides A (1) and B (2), have been isolated from the EtOAc extract of the sea urchin-derived Bacillus sp. along with the known cyclo(-L-pro-L-val-) (3), cyclo(-L-pro-L-tyr-) (4), cyclo(-L-pro-L-phe-) (5). These structures were elucidated by extensive spectroscopic methods. Furthermore, the absolute configurations of the amino acid residues were determined using Marfey's method. Compound 1 displayed weak antifungal activity against Aspergillus niger.
Keywords: Antifungal activity / Bacillus sp / Diketopiperazine derivative
URI: http://hdl.handle.net/10069/24767
ISSN: 00092363
DOI: 10.1248/cpb.59.106
Rights: (c) 2011 The Pharmaceutical Society of Japan
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/24767

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