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Leptin to high-molecular-weight adiponectin ratio is independently correlated with carotid intima-media thickness in men, but not in women.


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Title: Leptin to high-molecular-weight adiponectin ratio is independently correlated with carotid intima-media thickness in men, but not in women.
Authors: Takamura, Noboru / Hayashida, Naomi / Hagane, Kyoko / Kadota, Koichiro / Yamasaki, Hironori / Abiru, Norio / Ozono, Yoshiyuki / Kamihira, Shimeru / Aoyagi, Kiyoshi / Ishibashi, Kiyomi / Nakazato, Mio / Maeda, Takahiro
Issue Date: Jun-2010
Citation: Biomarkers, 15(4), pp.340-344; 2010
Abstract: BACKGROUND: The leptin:adiponectin ratio (L:A ratio) is an independent predictor of carotid intima-media thickness (CIMT). OBJECTIVE: To evaluate whether the leptin:high-molecular-weight adiponectin ratio (L:HA ratio) is associated with CIMT in the general population. METHODS: We investigated the relationship between the L:HA ratio and CIMT in 233 Japanese study participants (106 men and 127 women). RESULTS: After adjustment for confounding factors, CIMT was significantly correlated with the log L:HA ratio (beta = 0.11, p = 0.014) in men, whereas no correlation was observed in women (beta = 0.01, p = 0.50). Conclusion: The L:HA ratio is closely correlated with CIMT in men, but not in women.
Keywords: Adiponectin / Carotid intima-media thickness / High-molecular-weight adiponectin
URI: http://hdl.handle.net/10069/25390
ISSN: 1354750X
DOI: 10.3109/13547501003735532
PubMed ID: 20345321
Rights: © 2010 Informa UK Ltd. / This is an electronic version of an article published in Biomarkers, 15(4), pp.340-344; 2010. Biomarkers is available online at: http://informahealthcare.com/doi/abs/10.3109/13547501003735532
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/25390

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