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Noncultured autologous adipose-derived stem cells therapy for chronic radiation injury.


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Title: Noncultured autologous adipose-derived stem cells therapy for chronic radiation injury.
Authors: Akita, Sadanori / Akino, Kozo / Hirano, Akiyoshi / Ohtsuru, Akira / Yamashita, Shunichi
Issue Date: 2010
Publisher: Hindawi Publishing
Citation: Stem Cells International, 2010, 532704
Abstract: Increasing concern on chronic radiation injuries should be treated properly for life-saving improvement of wound management and quality of life. Recently, regenerative surgical modalities should be attempted with the use of noncultured autologous adipose-derived stem cells (ADSCs) with temporal artificial dermis impregnated and sprayed with local angiogenic factor such as basic fibroblast growth factor, and secondary reconstruction can be a candidate for demarcation and saving the donor morbidity. Autologous adipose-derived stem cells, together with angiogenic and mitogenic factor of basic fibroblast growth factor and an artificial dermis, were applied over the excised irradiated skin defect and tested for Patients who were uneventfully healed with minimal donor-site morbidity, which lasts more than 1.5 years.
URI: http://hdl.handle.net/10069/25613
ISSN: 16879678
DOI: 10.4061/2010/532704
PubMed ID: 21151652
Rights: Copyright © 2010 Sadanori Akita et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/25613

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