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Availability of Cardio-Ankle Vascular Index (CAVI) as a Screening Tool for Atherosclerosis

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Title: Availability of Cardio-Ankle Vascular Index (CAVI) as a Screening Tool for Atherosclerosis
Authors: Kadota, Koichiro / Takamura, Noboru / Aoyagi, Kiyoshi / Yamasaki, Hironori / Usa, Toshiro / Nakazato, Mio / Maeda, Takahiro / Wada, Mitsuhiro / Nakashima, Ken-ichiro / Abe, Koh / Takeshima, Fuminao / Ozono, Yoshiyuki
Issue Date: 25-Jan-2008
Publisher: The Japanese Circulation Society / 日本循環器学会
Citation: Circulation Journal, 72(2), pp.304-308; 2008
Abstract: Background: A novel index, the cardio-ankle vascular index (CAVI), which reflects the stiffness of the aorta, femoral artery, and tibial artery, was recently developed by measuring brachial-ankle pulse wave velocity and blood pressure. Methods and Results: In the present study 1,014 Japanese adults from the general population were screened to clarify the correlation between CAVI and other existing markers related to atherosclerosis, including carotid intima-media thickness (CIMT) and homocysteine (HCY). CAVI was strongly associated with age in both men and women. After adjustment for age and sex, CAVI was correlated with systolic and diastolic blood pressures. In addition, CAVI was significantly correlated with total cholesterol hemoglobin A1c and total HCY, as well as CIMT. Conclusion: CAVI is an appropriate screening tool for atherosclerosis, but further studies are needed to establish a convenient and effective screening system using it.
Keywords: Atherosclerosis / Cardio-ankle vascular index (CAVI) / Carotid intima-media thickness (CIMT) / Homocysteine (HCY)
URI: http://hdl.handle.net/10069/25879
ISSN: 13469843
DOI: 10.1253/circj.72.304
Type: Journal Article
Text Version: publisher
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/25879

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