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Long-term follow-up of adalimumab monotherapy for rheumatoid arthritis in Japanese patients: a report of six cases


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Title: Long-term follow-up of adalimumab monotherapy for rheumatoid arthritis in Japanese patients: a report of six cases
Authors: Ichinose, Kunihiro / Origuchi, Tomoki / Kawashiri, Shin-ya / Iwamoto, Naoki / Fujikawa, Keita / Aramaki, Toshiyuki / Kamachi, Makoto / Arima, Kazuhiko / Tamai, Mami / Nakamura, Hideki / Ida, Hiroaki / Kawakami, Atsushi / Eguchi, Katsumi
Issue Date: Feb-2012
Publisher: Springer Verlag
Citation: Rheumatology International, 32(2), 483-187; 2012
Abstract: We present six cases of patients with Japanese rheumatoid arthritis (RA) treated with a tumor necrosis factor (TNF)-alpha blocking agent, adalimumab as monotherapy for 220 weeks. All six patients were women, and the median age was 54.0 ± 7.07 years old. The median duration of the disease was 7.43 ± 11.1 years, and the median disease activity score (DAS28-CRP) was 5.35 ± 0.69. Three of six patients were able to continue to receive this treatment for 220 weeks successfully, and the DAS28-CRP decreased to 1.89 ± 0.75. Two patients withdrew because of lack of efficacy, and one patient withdrew because of adverse events (non-Hodgkin lymphoma). Adalimumab resulted in a sustained clinical response in RA patients during 220-week follow-up.
Keywords: Adalimumab / DAS28-CRP / Long-term / Rheumatoid arthritis (RA)
URI: http://hdl.handle.net/10069/28795
ISSN: 01728172
DOI: 10.1007/s00296-010-1770-1
Rights: © 2011 Springer-Verlag / The original publication is available at springerlink.com.
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/28795

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