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Evaluation of the Presumable Incidence of Pancreatic Islet Cell Transplantation in Nagasaki

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Title: Evaluation of the Presumable Incidence of Pancreatic Islet Cell Transplantation in Nagasaki
Authors: Tanaka, Takayuki / Kuroki, Tamotsu / Adachi, Tomohiko / Okamoto, Tatsuya / Ono, Shinichiro / Abiru, Norio / Kawakami, Atsushi / Eguchi, Susumu
Issue Date: Jul-2012
Publisher: Nagasaki University School of Medicine / 長崎大学医学部
Citation: Acta medica Nagasakiensia, 57(2), pp.45-48; 2012
Abstract: Background Pancreatic islet cell transplantation (ICT) is one of the standard treatments for type I diabetes mellitus (T1DM), based on the Edmonton protocol of 2000.1) A previous report presented the expected annual incidence of ICT recipients in Nagasaki Prefecture in 2006.2),3) This report presents variations in the background of T1DM patients followed in this department and evaluated the current annual incidence of possible ICT recipients. Methods This study reviewed 128 TIDM patients followed at Nagasaki University Hospital in 2011, examined the annual incidence of ICT recipients based on the Japanese Islet Transplant Registry criteria and the population of Nagasaki, and compared those results in 2011 with those in 2006. In addition, the annual numbers of cardiac death donors who were considered ICT donor candidates in Nagasaki over this period were examined. Results The proportion of candidates suitable to be recipients in Nagasaki changed from 4% (3/75) in 2006 to 7.8% (10/128) in 2011. The estimated incidence of suitable recipient candidates increased from 1.0 per year to 1.8 per year. On the other hand, though the estimated number of donor candidates was 2.6 per year, which was the mean for the 7 years between 2002 and 2009, only one candidate was reported in 2010 and no candidate was reported in 2011 in Nagasaki. Conclusion Although securing donors has become difficult due to a new law on organ transplantation, the demand for ICT has increased and may continue increase in the future. Therefore, it is important to confirm the criteria in brain dead donors to determine whether the pancreas should be directed to the pancreatic transplantation or pancreatic islet transplantation.
Keywords: pancreatic islet cell transplant / type I diabetes mellitus / Nagasaki
URI: http://hdl.handle.net/10069/28960
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 57, No. 2

Citable URI : http://hdl.handle.net/10069/28960

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