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Comparison of Postoperative Morbidity in Elderly Patients who Underwent Pancreatic Resection

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Title: Comparison of Postoperative Morbidity in Elderly Patients who Underwent Pancreatic Resection
Authors: Nanashima, Atsushi / Abo, Takafumi / Nonaka, Takashi / Hidaka, Shigekazu / Takeshita, Hiroaki / Morisaki, Tomohito / Uehara, Ryohei / Ohnita, Ken / Takeshima, Fuminao / Isomoto, Hajime / Sawai, Terumitsu / Nakao, Kazuhiko / Nagayasu, Takeshi
Issue Date: 18-May-2012
Publisher: H.G.E. Update Medical Publishing Ltd.
Citation: Hepato-Gastroenterology, 59(116), pp.1141-1146; 2012
Abstract: Background/Aims: Operative indications for pancreatectomy in elderly patients with pancreatic disease remain controversial. We examined clinicopathological characteristics and early outcomes in each generation of 147 patients who underwent pancreatectomy. Methodology: Patients were divided into four groups: Group 1 (n=15, 10%), young patients <50 years old; Group 2 (n=65; 44%), patients at 50-69 years old; Group 3 (n=61, 42%), patients at 70-79 years old and Group 4 (n=6, 4%), elderly patients <80 years old. Clinicopathological and surgical parameters were examined, including estimation of physiological ability and surgical stress consisting of preoperative risk score (PRS), surgical stress score (SSS) and comprehensive risk score (CRS). Results: Prevalence of comorbidity and American Society of Anesthesiologists (ASA) score increased significantly with increasing patient age (p<0.05). Extent of pancreatectomy and lymphadenectomy did not differ between groups and surgical records were similar. Tumor stage, post-operative course and complications were similar between groups. PRS and CRS increased significantly with increasing patient age (p<0.05) but SSS did not. Univariate analysis identified presence of systemic comorbidity, ASA score =2 and PRS =0.32 as factors associated with postoperative complications, but no independent predictive parameters were identified on multivariate analysis. Conclusions: Careful management and adequate decisions regarding pancreatectomy upon identification of comorbidity, ASA score and PRS are important in elderly patients with pancreatic disease before pancreatectomy.
Keywords: Complications / E-PASS / Elderly patients / Outcomes / Pancreatectomy
URI: http://hdl.handle.net/10069/29173
ISSN: 01726390
DOI: 10.5754/hge10777
PubMed ID: 22580667
Rights: © H.G.E. Update Medical Publishing S.A.
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/29173

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