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Amelanotic melanoma of the mandible: A case report

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Title: Amelanotic melanoma of the mandible: A case report
Authors: Kawasaki, Goro / Yanamoto, Souichi / Yoshitomi, Izumi / Mizuno, Akio / Fujita, Shuichi / Umeda, Masahiro
Issue Date: Nov-2011
Publisher: Elsevier
Citation: Oral Science International, 8(2), pp.60-63; 2011
Abstract: Amelanotic melanoma of the oral mucosa is extremely rare. We describe herein our experience of amelanotic melanoma arising in the mandibular mucosa. An 85-year-old woman was referred to our clinic with swelling of the left lower gingival mucosa. The histopathological diagnosis was amelanotic melanoma, as determined by immunohistochemical examination. The tumor cells were positive for S-100, Melan-A, HMB-45, and vimentin. The patient declined surgical treatment, so she received irradiation therapy. At a total dose of 10. Gy, the patient exhibited lassitude, so we terminated radiotherapy. Bleeding from the tumor persisted, and the patient developed anemia and hypouresis. She also contracted pneumonia. The patient's general condition worsened, and she died.
Keywords: Amelanotic melanoma / Immunohistochemistry / Oral mucosa
URI: http://hdl.handle.net/10069/29867
ISSN: 13488643
DOI: 10.1016/S1348-8643(12)00002-X
Rights: © 2012 Japanese Stomatological Society. / NOTICE: this is the author’s version of a work that was accepted for publication in Oral Science International. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Oral Science International, 8, 2(2011)
Type: Journal Article
Text Version: author
Appears in Collections:Articles in academic journal

Citable URI : http://hdl.handle.net/10069/29867

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