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A case of acinar cell carcinoma of the pancreas


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Title: A case of acinar cell carcinoma of the pancreas
Authors: Tominaga, Tetsuro / Nanashima, Atsushi / Abo, Takafumi / Wakata, Kouki / Hamasaki, Keiko / Kunizaki, Masaki / To, Kazuo / Hidaka, Shigekazu / Takeshita, Hiroaki / Kinoshita, Naoe / Kudo, Takashi / Nagayasu, Takeshi
Issue Date: Apr-2013
Publisher: Nagasaki University School of Medicine / 長崎大学医学部
Citation: Acta medica Nagasakiensia, 58(1), pp.25-28; 2013
Abstract: Background Acinar cell carcinoma (ACC) is a very rare malignancy and represents only 1% to 2% of pancreatic exocrine carcinomas. At the time of diagnosis, 75% of ACC are resectable. Reliable data concerning effective adjuvant chemotherapy has not been established. Case presentation A 30-mm tumor in the pancreatic tail was incidentally discovered by computed tomography in a 71-yearold man. Several swollen lymph nodes were seen around the main tumor. Endoscopic retrograde cholangiopancreatography (ERCP) revealed disruption of the main pancreatic duct. The patient underwent curative resection (R0) with distal pancreatectomy and node dissection. Histopathological examination revealed ACC with lymph node metastases; adjuvant chemotherapy was performed with gemcitabine after surgery. Twelve months later, the patient showed no sign of recurrence. Conclusion The prognosis of ACC is dismal, although compared to ductal adenocarcinoma, the mean survival appears to be longer. Patients with advanced-stage ACC might benefit from gemcitabine-based adjuvant chemotherapy.
Keywords: acinar cell carcinoma / adjuvant chemotherapy / operation
URI: http://hdl.handle.net/10069/32067
ISSN: 00016055
Type: Departmental Bulletin Paper
Text Version: publisher
Appears in Collections:Volume 58, No. 1

Citable URI : http://hdl.handle.net/10069/32067

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